Abstract
The Drosophila Gal4/UAS system allows the expression of any gene of interest in restricted domains. We devised a genetic strategy, based on the P-element replacement and UAS- y + techniques, to generate Gal4 lines inserted in Hox genes of Drosophila that are, at the same time, mutant for the resident genes. This makes possible to express different wild-type or mutant Hox proteins in the precise domains of Hox gene expression, and thus to test the functional value of these proteins in mutant rescue experiments.
Author supplied keywords
Cite
CITATION STYLE
De Navas, L., Foronda, D., Del Saz, D., & Sánchez-Herrero, E. (2014). A genetic strategy to obtain P-Gal4 elements in the Drosophila Hox genes. Methods in Molecular Biology, 1196, 49–57. https://doi.org/10.1007/978-1-4939-1242-1_4
Register to see more suggestions
Mendeley helps you to discover research relevant for your work.
