Mammalian genomes encode numerous natural antisense transcripts, but the function of these transcripts is not well understood. Functional validation studies indicate that antisense transcripts are not a uniform group of regulatory RNAs but instead belong to multiple categories with some common features. Recent evidence indicates that antisense transcripts are frequently functional and use diverse transcriptional and post-transcriptional gene regulatory mechanisms to carry out a wide variety of biological roles. © 2009 Macmillan Publishers Limited. All rights reserved.
CITATION STYLE
Faghihi, M. A., & Wahlestedt, C. (2009, September). Regulatory roles of natural antisense transcripts. Nature Reviews Molecular Cell Biology. https://doi.org/10.1038/nrm2738
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