PPM1D mutations in circulating white blood cells and the risk for ovarian cancer

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Abstract

We compared the frequency of PPM1D mutation in the white blood cells from 1295 ovarian cancer case patients and 834 control subjects. We found a truncating mutation in 20 case patients vs 1 control subject (odds ratio [OR] = 13.07; 95% confidence interval [CI] = 1.75 to 97.55; P

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Akbari, M. R., Lepage, P., Rosen, B., McLaughlin, J., Risch, H., Minden, M., & Narod, S. A. (2014). PPM1D mutations in circulating white blood cells and the risk for ovarian cancer. Journal of the National Cancer Institute, 106(1). https://doi.org/10.1093/jnci/djt323

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