Serum cardiac markers are inversely associated with VO 2 max of amateur athletes in response to endurance training adaptations

Abstract

Background The influence of endurance training intensity and adaptation on serum cardiac markers is poorly understood and controversial; however, no enough data observed the association of serum cardiac markers with VO 2 max. Therefore, we aimed to investigate whether serum cardiac markers are associated with maximum oxygen consumption (VO 2 max) in response to 12-week endurance training on amateur athletes. Methods 15 apparently healthy male amateur athletes with 19.47 ± 1.30 years of age were recruited and participated in endurance training with 70%-80% maximal heart rate intensity for 35 min per session for the first week and 2 min increments each week from the second to the last week for a period of 12 weeks. VO 2 max and serum cardiac markers (lactate dehydrogenase [LDH], creatine kinase myocardial band (CK-MB) and cardiac troponin I [CTnI]) were assessed at the beginning of the training and after 12-week endurance training. Results The result of CTnI indicated significantly (p < 0.01) and inversely (r = a ' 0.466) correlated with VO 2 max and CK-MB indicated significantly (p < 0.01) and inversely associated with VO 2 max (r = a ' 0.536) with moderate relationship. However, we did not find a significant association on LDH (p > 0.05) with VO 2 max in response to endurance training adaptation. Conclusion Our finding confirms our hypothesis that serum cardiac markers are inversely associated with estimated VO 2 max in response to endurance training adaptation.