Purpose: This study aimed to investigate the association between serum levels of cortisol and dehydroepiandrosterone sulfate (DHEA-s) and sickness absence over 2 years in Japanese male workers. Method: A baseline survey including questions about health behavior, along with blood sampling for cortisol and DHEA-s, was conducted in 2009. In total, 429 men (mean ± SD age, 52.9 ± 8.6 years) from whom blood samples were collected at baseline were followed until December 31, 2011. The hazard ratios (HR) and 95% confidence intervals (CI) for sickness absence were calculated using a Cox proportional hazard model, adjusted for potential confounders. Results: Among 35 workers who took sickness absences, 31 had physical illness. A high cortisol to DHEA-s ratio increased the risk of sickness absence (crude HR = 2.68, 95% CI 1.12–6.41; adjusted HR = 3.33, 95% CI 1.35–8.20). The cortisol to DHEA-s ratio was linearly associated with an increased risk of sickness absence (p for trend
CITATION STYLE
Hirokawa, K., Fujii, Y., Taniguchi, T., Takaki, J., & Tsutsumi, A. (2018). Association Between Cortisol to DHEA-s Ratio and Sickness Absence in Japanese Male Workers. International Journal of Behavioral Medicine, 25(3), 362–367. https://doi.org/10.1007/s12529-017-9700-1
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