The impact of frequent cystoscopy on surgical care and cancer outcomes among patients with low-risk, non–muscle-invasive bladder cancer

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Abstract

Background: Surveillance recommendations for patients with low-risk, non–muscle-invasive bladder cancer (NMIBC) are based on limited evidence. The objective of this study was to add to the evidence by assessing outcomes after frequent versus recommended cystoscopic surveillance. Methods: This was a retrospective cohort study of patients diagnosed with low-risk (low-grade Ta (AJCC)) NMIBC from 2005 to 2011 with follow-up through 2014 from the Department of Veterans Affairs. Patients were classified as having undergone frequent versus recommended cystoscopic surveillance (>3 vs 1-3 cystoscopies in the first 2 years after diagnosis). By using propensity score-adjusted models, the authors estimated the impact of frequent cystoscopy on the number of transurethral resections, the number of resections without cancer in the specimen, and the risk of progression to muscle-invasive cancer or bladder cancer death. Results: Among 1042 patients, 798 (77%) had more frequent cystoscopy than recommended. In adjusted analyses, the frequent cystoscopy group had twice as many transurethral resections (55 vs 26 per 100 person-years; P

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Schroeck, F. R., Lynch, K. E., Li, Z., MacKenzie, T. A., Han, D. S., Seigne, J. D., … Goodney, P. P. (2019). The impact of frequent cystoscopy on surgical care and cancer outcomes among patients with low-risk, non–muscle-invasive bladder cancer. Cancer, 125(18), 3147–3154. https://doi.org/10.1002/cncr.32185

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