Anatomo-pathology

Abstract

Knowledge of the anatomical and pathological features of the prostate and its neoplastic proliferations is essential for the diagnosis and treatment of prostate cancer. Ongoing research continues to bring forward new and important insights into the anatomy of the prostate and a better understanding of prostate cancer histopathology. Recent advances in the identification of histological markers of aggressive disease and tumor grading provide additional prognostic information to guide clinical decision making and have been incorporated in a new prostate cancer grading system. With the increased availability of modern imaging modalities, clinicians have become more aware of the importance of prostate cancers in the anterior region of the prostate, particularly in the context of active surveillance of patients with a presumed low risk prostate cancer. This chapter addresses these advances in the context of an overview of the anatomo-pathology of the prostate.