Absolute and Relative Bioavailability

Abstract

Attaining desired blood drug concentration and, consequently, augmenting the bioavailability of poorly absorbed drugs have always been an essential aspect for the pharmaceutical agency. The achievement of this target gives positive economic benefits as reducing drug dosage and medical impacts in decreasing toxicity and bacterial resistance in case of antimicrobials. Various factors may reduce the availability of drugs. There are numerous ways to estimate bioavailability. Various software's models have been developed to simplify such analyses. The newly developed programs should provide a range of modules for pharmacokinetic and pharmacodynamic analysis with a more user-friendly interface.