Chemical Constituents of Sauropus androgynus and Evaluation of its Antioxidant Activity

Abstract

Background and Objective: Antioxidants are involved in the prevention of cancer, aging and variety of diseases. The scientific community has begun to interest in the identification, recovery and enhanced performance of natural antioxidant principles from plant sources. The objective of this present study is also guide to the invention of new antioxidant sources from Sauropus androgynus. Materials and Methods: The antioxidant activity of plant material was assayed by DPPH radical scavenging assay and also the chemical compositions were investigated using GCMS-QP-2010 plus gas chromatography-mass spectrometry. Vitamins like ascorbic acid, riboflavin and thiamine were estimated according to the method of Koche. Results: Results showed that about 20 phyto active components are obtain from the leaves having vitamin C as major component while seed contains 10 components having fatty acids as major components. The leaf and seed extract showed significant DPPH scavenging activity (IC50 values are 49.62±2.52 and 52.47±2.21 µg mLG1 ) compared with the values obtained for ascorbic acid standard (IC50 value 48.82±1.80). Conclusion: From the results obtained it was concluded that Sauropus androgynus contain various phytochemicals, justifying their use for various human ailments.