Non-covalent supported of L-proline on Graphene Oxide/Fe3O4 Nanocomposite: A novel, highly efficient and superparamagnetically separable catalyst for the synthesis of bis-pyrazole derivatives

Abstract

A superparamagnetic graphene oxide/Fe3O4/L-proline nano hybrid that was obtained from the non-covalent immobilization of L-proline on graphene oxide/Fe3O4 nanocomposite was used as a new magnetically separable catalyst for the efficient synthesis of 4,4-(arylmethylene)bis(1H-pyrazol-5-ol) derivatives. The prepared heterogeneous catalyst was characterized using FTIR, TGA, DTG, XRD, TEM, SEM, and elemental analysis techniques. Short reaction times (5–15 min), excellent yields (87–98%), and simple experimental procedure with an easy work-up are some of the advantages of the introduced catalyst.