Supercritical fluid technology and supercritical fluid chromatography for application in ginseng extracts

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Abstract

This research review deals with the study of the scientific articles, published during the last two decades that are devoted to the extraction of ginsenosides from different types of ginseng with the use of supercritical CO 2 (SC - CO 2 ). Different types of ginseng are being the object of investigation including Panax ginseng C.A. Meyer, Brazilian ginseng (Pfaffia paniculata, Pfaffia glomerata, Hebanthe eriantha) and North American ginseng (Panax quinquefolius). It was shown that the extraction and fractionation of Panax ginseng C.A. Meyer using SC-CO 2 technology is a very effective way for extracting biologically active plant components, such as ginsenosides, kudinosides, polysaccharides, polyphenolic compounds and stauntosides. In addition, it was exhibited that SC-CO 2 technology could increase considerably the yield in antioxidant fractions in which the concentration of bioactive components of a P. ginseng C.A. Meyer are high. At last, this review also considers the application of supercritical CO 2 fluid chromatography for Panax ginseng. The review aspired to investigate the contents and to compare other ways of extraction with supercritical extraction and to show its efficiency and also use of new “green technologies”.

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Razgonova, M. P., Zakharenko, A. M., Kalenik, T. K., Nosyrev, A. E., Stratidakis, A. K., Mezhuev, Y. O., … Golokhvast, K. S. (2019). Supercritical fluid technology and supercritical fluid chromatography for application in ginseng extracts. Farmacia. Romanian Society for Pharmaceutical Sciences. https://doi.org/10.31925/farmacia.2019.2.2

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