Large-scale and high-throughput genomics research needs reliable and comprehensive genome-wide promoter annotation resources. We have conducted a systematic investigation on how to improve mammalian promoter prediction by incorporating both transcript and conservation information. This enabled us to build a better multispecies promoter annotation pipeline and hence to create CSHLmpd (Cold Spring Harbor Laboratory Mammalian Promoter Database) for the biomedical research community, which can act as a starting reference system for more refined functional annotations.
CITATION STYLE
Xuan, Z., Zhao, F., Wang, J., Chen, G., & Zhang, M. Q. (2005). Genome-wide promoter extraction and analysis in human, mouse, and rat. Genome Biology, 6(8).
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