Abstract
Age-related macular degeneration (AMD) is a complex, multifactorial disease associated with environmental and genetic factors. This review emphasizes the clinical impact of the major genetic factors mainly located in the complement factor H gene and on the 10q26 locus, and their current and future implications for the management of AMD. © 2011 S. Karger AG, Basel.
Author supplied keywords
- Age-related macular degeneration
- Age-related maculopathy
- Age-related maculopathy susceptibility 2 gene (ARMS2)
- Asian
- Atrophic age-related macular degeneration
- Complement component 2, 3, 9 (C2, C3, C9)
- Complement factor H gene (CFH)
- Exudative age-related macular degeneration
- Genetic factors
- Genetic profiling
- Genome-wide association studies
- HtrA serine peptidase 1 gene (HTRA1)
- LOC387715
- Missing heritability
- Personalized medicine
Cite
CITATION STYLE
APA
Leveziel, N., Tilleul, J., Puche, N., Zerbib, J., Laloum, F., Querques, G., & Souied, E. H. (2011, September). Genetic factors associated with age-related macular degeneration. Ophthalmologica. https://doi.org/10.1159/000328981
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