The RNA infrastructure connects RNA-based functions. With transcription-to-translation processing forming the core of the network, we can visualise how RNA-based regulation, cleavage and modification are the backbone of cellular function. The key to interpreting the RNA-infrastructure is in understanding how core RNAs (tRNA, mRNA and rRNA) and other ncRNAs operate in a spatial-temporal manner, moving around the nucleus, cytoplasm and organelles during processing, or in response to environmental cues. This chapter summarises the concept of the RNA-infrastructure, and highlights examples of RNA-based networking within prokaryotes and eukaryotes. It describes how transcription-to-translation processes are tightly connected, and explores some similarities and differences between prokaryotic and eukaryotic RNA networking. © 2011 Landes Bioscience and Springer Science+Business Media, LLC.
CITATION STYLE
Collins, L. J. (2011). The RNA infrastructure: An introduction to ncRNA networks. Advances in Experimental Medicine and Biology, 722, 1–19. https://doi.org/10.1007/978-1-4614-0332-6_1
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