Total synthesis of an indolizidine alkaloid, (+)-Ipalbidine, by means ofanintramolecular McMurry coupling reaction

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Abstract

An indolizidine alkaloid, (+)-ipalbidine, exhibiting a non-addictive analgesic activity, was synthesized in an optically active form, by employing an intramolecular McMurry coupling reaction as a key step.

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Honda, T., Namiki, H., Nagase, H., & Mizutani, H. (2003). Total synthesis of an indolizidine alkaloid, (+)-Ipalbidine, by means ofanintramolecular McMurry coupling reaction. Arkivoc, 2003(8), 188–198. https://doi.org/10.3998/ark.5550190.0004.819

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