Oral corticosteroids for bronchiectasis (stable and acute exacerbations)

Abstract

Background: Inflammation plays a significant role in the pathophysiology of bronchiectasis. Two small studies have shown small benefits from inhaled corticosteroids and oral corticosteroids may be of benefit in bronchiectasis. Objectives: To determine the efficacy of oral corticosteroids in acute and stable bronchiectasis. Search methods: The Cochrane Airways Group Specialised Register was searched and bibliographies of retrieved papers were checked. Searches are current as of May 2011. Selection criteria: Only randomised controlled trials were considered. Data collection and analysis: No trials met the inclusion criteria for the review. Main results: No randomised controlled trials were identified. Authors' conclusions: There are no randomised trials upon which to base recommendations about the use of oral corticosteroids in acute or stable bronchiectasis.