Refined Analysis of Prostate-specific Antigen Kinetics to Predict Prostate Cancer Active Surveillance Outcomes

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Abstract

In this report, we looked at whether repeat prostate-specific antigen (PSA) measurements, or PSA kinetics, improve prediction of biopsy outcomes in men using active surveillance to manage localized prostate cancer. We found that in a large multicenter active surveillance cohort, PSA kinetics improves the prediction of surveillance biopsy outcome.

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Cooperberg, M. R., Brooks, J. D., Faino, A. V., Newcomb, L. F., Kearns, J. T., Carroll, P. R., … Zheng, Y. (2018). Refined Analysis of Prostate-specific Antigen Kinetics to Predict Prostate Cancer Active Surveillance Outcomes. European Urology, 74(2), 211–217. https://doi.org/10.1016/j.eururo.2018.01.017

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