The Role of Echinocandins in Candida Biofilm-Related Vascular Catheter Infections: In Vitro and in Vivo Model Systems

Abstract

Candida biofilm-associated infections of central venous catheters are a challenging therapeutic problem. Recent in vitro and in vivo studies of the structure, formation, pathogenesis, and treatment establish a rationale for new approaches to management of these tenacious infections.