Accelerated nodulosis (AN) is a potential complication of methotrexate (MTX) therapy for rheumatoid arthritis (RA). We report on a 62-year old man affected by seropositive RA who developed AN after five months of MTX treatment. MTX-dose reduction was followed by rapid regression of the skin nodules. The Authors describe the typical features of AN and discuss on the pathogenetic mechanisms.
CITATION STYLE
Filosa, G., Salaffi, F., & Bugatti, L. (1999). Accelerated nodulosis during methotrexate therapy for refractory rheumatoid arthritis: A case report. In Advances in Experimental Medicine and Biology (Vol. 455, pp. 521–524). Kluwer Academic/Plenum Publishers. https://doi.org/10.1007/978-1-4615-4857-7_77
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