Modern developments in time-lapse microscopy enable the observation of a variety of processes exhibited by viruses. The dynamic nature of these processes requires the tracking of viruses over time to explore the spatio-temporal relationships. In this work, we developed deterministic and probabilistic approaches for multiple virus tracking. A quantitative comparison based on synthetic image sequences was carried out to evaluate the performance of the different algorithms. We have also applied the algorithms to real microscopy images of HIV-1 particles and have compared the tracking results with ground truth obtained from manual tracking. It turns out that the probabilistic approach outperforms the deterministic schemes.
CITATION STYLE
Godinez, W. J., Lampe, M., Wörz, S., Müller, B., Eils, R., & Rohr, K. (2007). Tracking of virus particles in time-lapse fluorescence microscopy image sequences. In Informatik aktuell (pp. 6–10). Kluwer Academic Publishers. https://doi.org/10.1007/978-3-540-71091-2_2
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