Abstract
The effect of bradykinin and kininase on renal function and the metabolism of bradykinin in the kidney were examined in isolated perfused rat kidney. In this experimental system, exogenous bradykinin did not affect the water and electrolyte handling by the kidney. Most of bradykinin and kininase in urine were derived from kidney but not from circulating medium. Kininase II may not have a major role in bradykinin destruction by the kidney.
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CITATION STYLE
Ogihara, T., Dupin, T., Nakane, H., Nakane, Y., Saruta, T., Misumi, J., & Mènard, J. (1986). Metabolism of bradykinin in isolated perfused rat kidney. Measurement of kininase activity in perfusate and urine. Advances in Experimental Medicine and Biology, 198 Pt A, 367–373. https://doi.org/10.1007/978-1-4684-5143-6_50
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