Copper-catalyzed transformation of alkyl nitriles to N -arylacetamide using diaryliodonium salts

Abstract

This work reports a simple and efficient method for the copper-catalyzed redox-neutral transformation of alkyl nitriles using eco-friendly diaryliodonium salts and leading to N-arylacetamides. The method features high efficiency, broad substrate scope and good functional group tolerance.