Aislamiento de cepas de Escherichia coli desde casos clínicos de infección vaginal: Asociación con otros microorganismos y susceptibilidad antibacteriana

Abstract

Objective: To determine the presence of Escherichia coli in vaginal fluids of women with vaginal infection and to study its antimicrobial susceptibility. Methods: 425 samples of women with clinical diagnosis of vaginal infection (cases) and 100 healthy women were studied (controls). The vaginal samples were studied by means of the criteria of Amsel and Nugent. Different methodologies were used to identify: Trichomonas vaginalis, Candida albicans, Gardnerella vaginalis, Chlamydia trachomatis, Mycoplasma hominis, Ureaplasma urealyticum, Neisseria gonorrhoeae, Mobiluncus sp., Streptococcus agalactiae, Enterococcus faecalis, enterobacterias, strict anaerobic Gram negative bacilli, Lactobacillus sp. and coagulase negative Staphylococcus. Results: 160 cases of vaginitis and 265 of vaginosis were observed. In vaginitis predominated C. albicans and T. vaginalis, and were isolated 27 E. coli strains. In the bacterial vaginosis, G. vaginalis and E. coli were the most common. The greater association was observed between G. vaginalis and E. coli. In 47 cases single E. coli was isolated. In the controls 6 E. coli strains were observed. The study of case-control demonstrated a OR: 4.7 (95% CI: 1.91-12.27). Isolated E. coli demonstrated sensitivity over 90% to cefotaxime, ciprofloxacin and amikacin. Conclusion: Single E. coli isolated could have a potential role in the pathogenia of the vaginal infection.