Factor XI Deficiency (FXID) alleles distribution in dairy cow population in Enrekang regency, South Sulawesi

Abstract

Factor XI Deficiency (FXID) is a genetic defect due to an autosomal recessive allele in dairy cows, thus cause a large economic and productivity loss in livestock. The purpose of this study was to identify the distribution of recessive alleles of FXID in dairy cows in Enrekang regency using the PCR method. A total of 80 DNA samples were isolated from the FH dairy cow blood sample collected from the Enrekang dairy farms (50 samples from Cendana district and 30 samples from Anggeraja District). All DNA samples were amplified by the PCR technique. The identification of the FXID carrier allele was calculated based on the genotype and allele frequencies. Results showed that 1 of 50 samples from Cendana district was FXID heterozygous while none of 30 samples from Anggeraja district showed FXID alleles. This study concluded that there was a normal heterozygous (Ff) FXID carrier in dairy cow population in Enrekang Regency with the allele frequency was 1.25%.