Disproportionate exposure to antibiotics in children at risk for invasive pneumococcal disease: Potential for emerging resistance and opportunity for antibiotic stewardship

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Abstract

We compared antibiotic prescribing for children with and those without an underlying chronic condition associated with increased risk for invasive pneumococcal disease. Children with a chronic condition had significantly greater cumulative exposure to antibiotics and higher rates of prescriptions per person-year than those without a chronic condition; this population is at increased risk for the emergence of multidrug-resist-ant pathogens.

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Barlam, T. F., Morgan, J. R., Kaplan, W. A., Outterson, K., & Pelton, S. I. (2019). Disproportionate exposure to antibiotics in children at risk for invasive pneumococcal disease: Potential for emerging resistance and opportunity for antibiotic stewardship. Journal of the Pediatric Infectious Diseases Society, 8(1), 63–65. https://doi.org/10.1093/jpids/pix070

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