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Association of the RTX proteins of Actinobacillus pleuropneumoniae with hemolytic, CAMP, and neutrophil-cytotoxic activities

Infection and Immunity
DOI: 10.1128/iai.60.5.2139-2142.1992
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Abstract

The immunoglobulin G from a monospecific rabbit antiserum to the 110-kDa RTX hemolysin of Actinobacillus pleuropneumoniae serotype 1 was used to determine that the related RTX proteins in isolates from serotypes 2 to 12 were also responsible for the hemolytic, CAMP, and neutrophil-cytotoxic activities produced by this bacterium. These proteins share common neutralizing epitopes.

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Devenish, J., Brown, J. E., & Rosendal, S. (1992). Association of the RTX proteins of Actinobacillus pleuropneumoniae with hemolytic, CAMP, and neutrophil-cytotoxic activities. Infection and Immunity. https://doi.org/10.1128/iai.60.5.2139-2142.1992

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