The mammalian immune system is specialized for the discrimination between self and nonself. The appearance of new macromolecules (or antigens) normally signifies a threat, such as an infection or malignant tumor. In these settings, the prompt destruction of antigen-bearing cells is a valuable adaptation. Unfortunately, the same defense mechanisms are also efficiently invoked by the clinical transplantation of potentially lifesaving organs. © 2008 Springer New York.
CITATION STYLE
Thistlethwaite, J. R., & Bruce, D. (2008). Rejection. In Surgery: Basic Science and Clinical Evidence: Second Edition (pp. 1737–1746). Springer New York. https://doi.org/10.1007/978-0-387-68113-9_82
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