Antioxidant and antimicrobial properties of 2-(4,5-dihydro-1H-pyrazol-1-yl) -pyrimidine and 1-carboxamidino-1H-pyrazole derivatives

Abstract

Five previously synthesized 4-trifuoromethyl-2-(5-aryl-3-styryl-1H-pyrazol- 1yl)-pyrimidines and six 5-aryl-3-styryl-1-carboxamidino-1H-pyrazole derivatives were screened for their antioxidant proprieties. The antioxidant activities were evaluated by using the DPPH and the HRP/luminol/H2O2 chemiluminescence assay systems and for their antimicrobial activity (MIC). The results were good for those series in some concentration in comparison with the standards. © 2010 Sociedade Brasileira de Química.