Evaluation and treatment of orgasmic dysfunction

Abstract

Orgasm is the third phase of the sexual response cycle. Orgasm also describes the cerebral process of pleasure that is most often associated with ejaculation. Oxytocin and prolactin rise during ejaculation and orgasm, though the hormonal control of orgasm has not been completely elucidated. The most common cause of orgasmic dysfunction is iatrogenic, due to selective serotonin reuptake inhibitors, although anorgasmia associated with delayed ejaculation is also described. Treatment of orgasmic dysfunction is evolving, as there are no FDA-approved medications currently available. Further research is necessary in all aspects of the science of orgasm, especially the treatment of orgasmic dysfunction.