What is the future of pharmacovigilance and How Can We Make It as Good as Possible? Get the ADR Phenotype “Right”

Abstract

Pharmacovigilance is a scientific discipline that is underrecognized in its importance for improving understanding of drug effects in humans. It excels as a vehicle for detecting safety concerns particularly those early in the post-market phase after prescription drug approval. This is the time in the life cycle of a drug when manufacturers are required by regulatory agencies to provide adverse drug reaction (ADR) reports and the time when clinicians are gaining experience with new agents and are more likely to report ADRs [20]. The reporting of cases of drug-induced harm and subsequent analysis of such data is a critical part of population health surveillance, given the frequency of the use of drug therapy as a medical intervention.