Uji Aktivitas Antibakteri Ekstrak Jahe Merah (Zingiber officinale var. Rubrum) dan Ekstrak Bawang Putih (Allium sativum) terhadap Streptococcus pyogenes dengan Metode Difusi Cakram

  • Sitepu J
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Abstract

ABSTRACT   Background: Infections and antimicrobial resistance remains a major public health worldwide. Therefore, studies regarding the natural therapeutic agent that is safe for humans and specific against bacteria are getting more interest. Objective: This study aimed to investigate the effectiveness of combination red ginger and garlic extract against Streptococcus pyogenes.   Methods: This was a laboratory experimental study. The red ginger and garlic extract obtained by maceration extraction method using 70% ethanol and antibacterial activity test was conducted by disk diffusion method. Results: : One way Anova test showed that red ginger extract in 75% and 100% concetrations have significant difference with the control. Garlic extract in 75% and 100% concentrations have significant difference with the control. The higher concentration result wider inhibition zona hambat both in red ginger and garlic extract. Otherwise, red ginger- garlic combination extract showed no significant difference with the control. The widest mean inhibitioin was shown in R50-G50 extract combination which is 2.45mm (±0.3). Post hoc LSD test showed that red ginger 100% that has significant difference with red ginger 25%, so did garlic extract. There was no significant difference between red ginger-garlic combination groups. Conclusion: Red ginger and garlic extract has no synergic effect against Streptococcus pyogenes.

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APA

Sitepu, J. N. (2023). Uji Aktivitas Antibakteri Ekstrak Jahe Merah (Zingiber officinale var. Rubrum) dan Ekstrak Bawang Putih (Allium sativum) terhadap Streptococcus pyogenes dengan Metode Difusi Cakram. Nommensen Journal of Medicine, 8(2), 77–81. https://doi.org/10.36655/njm.v8i2.899

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