One new monoterpenoid glycoside, myresculoside (1), and eleven known compounds, were isolated from methanol extract of Myrica esculenta leaves by repeated column chromatography. The effects of these compounds on angiotensin I-converting enzyme (ACE) inhibition were investigated. Compounds 3 and 4 showed the most potent ACE inhibition with rates of 29.97% and 25.63% at concentration of 100 μM, respectively. Compounds 5, 6, and 11 showed weak activity with inhibitory rates of 0.07-1.41% at concentration of 100 μM. © 2010 Pharmaceutical Society of Japan.
CITATION STYLE
Nhiem, N. X., Van Kiem, P., Van Minh, C., Tai, B. H., Cuong, N. X., Thu, V. K., … Kim, Y. H. (2010). A new monoterpenoid glycoside from Myrica esculenta and the inhibition of angiotensin I-converting enzyme. Chemical and Pharmaceutical Bulletin, 58(10), 1408–1410. https://doi.org/10.1248/cpb.58.1408
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