Depressed mood, glycaemic control and functional capacity in overweight/obese men with and without type 2 diabetes

Abstract

Objective. To determine whether there were differences in depressed mood between overweight/obese men with and without type 2 diabetes (T2DM) and to examine any associations between depressed mood, physical functioning, and glycaemic control in overweight/obese men with and without T2DM. Methods. Fifty seven overweight/obese men with (n=19, age=54.2±7.4 yrs, BMI=32.3±6.7 kgṡm-2) and without T2DM (n=38, age=51.1±6.8 yrs, BMI=29.9±4.5kgṡm-2, p>0.05 between groups) participated. The men completed measures of depressed mood and health-related quality of life (HRQL) and underwent the following assessments: fasting blood lipids and glucose, HbA1c, anthropometric measurements, VO 2peak, muscle strength, and physical function. Results: Compared to men without T2DM, men with T2DM had higher depressed mood (p=0.05, η2=0.07), as well as lower perceived general health (p <0.01, η2=0.13). In those with T2DM, depressed mood was highly correlated with most HRQL subscales. For the combined cohort, depressed mood was correlated with fasting glucose (r=0.31, p=0.012) but not the functional measures. Conclusions: Men with T2DM have higher levels of depressed mood compared to men without T2DM. Glycaemic control, but not functional capacities, is associated with depressed mood in the study cohort. © 2012 Levinger et al.; licensee BioMed Central Ltd.