Background: Headache symptoms self-reported by migraine patients are largely congruent with the clinician-used diagnostic criteria, but not always so. Patients' self-reports of headache symptoms might offer additional clues to characterize migraine with (MA) and without (MO) aura more precisely. Methods: Firstly, we invited 324 participants with a life-long headache attack to answer an item-matrix measuring symptoms of primary headaches, then we performed both exploratory and confirmatory factor analyses to their answers and refined a headache symptom questionnaire. Secondly, we applied this questionnaire to 28 MA and 52 MO patients. Results: In participants with a life-long headache, we refined a 27-item, structure-validated headache symptom questionnaire, with four factors (scales) namely the Somatic /Aura Symptoms, Gastrointestinal and Autonomic Symptoms, Tightness and Location Features, and Prodromal/Aggravating Symptoms. Further, we found that MA patients reported higher than did MO patients on the Somatic/Aura Symptoms and Tightness and Location Features scales. Conclusions: Compared to MO, MA was conferred with more prominent tightness and location features besides its higher somatic or aura symptoms. Patients' self-reports of headache symptoms might offer more clues to distinguish two types of migraine besides their clinician-defined criteria.
CITATION STYLE
Wang, J., Zhang, B., Shen, C., Zhang, J., & Wang, W. (2017). Headache symptoms from migraine patients with and without aura through structure-validated self-reports. BMC Neurology, 17(1). https://doi.org/10.1186/s12883-017-0973-4
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