Actomyosin networks and tissue morphogenesis

161Citations
Citations of this article
378Readers
Mendeley users who have this article in their library.

Abstract

Tissue morphogenesis is driven by coordinated cellular deformations. Recent studies have shown that these changes in cell shape are powered by intracellular contractile networks comprising actin filaments, actin cross-linkers and myosin motors. The subcellular forces generated by such actomyosin networks are precisely regulated and are transmitted to the cell cortex of adjacent cells and to the extracellular environment by adhesive clusters comprising cadherins or integrins. Here, and in the accompanying poster, we provide an overview of the mechanics, principles and regulation of actomyosin-driven cellular tension driving tissue morphogenesis. © 2014. Published by The Company of Biologists Ltd.

Cite

CITATION STYLE

APA

Munjal, A., & Lecuit, T. (2014). Actomyosin networks and tissue morphogenesis. Development (Cambridge), 141(9), 1789–1793. https://doi.org/10.1242/dev.091645

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free