• Hexavalent chromium (salt) is a form of chromium responsible for sensitization and contact dermatitis in chromate allergy. • Exposure to chromium is often occupational and is commonly seen among building workers handling cement, leather workers, electroplaters, welders, and painters. • Addition of ferrous sulfate has reduced the incidence of chromate allergy in the Scandinavian countries, since it decreases the concentration of hexavalent chromate in cement. • Simple office-based tests are helpful in detecting chromium in objects. • Patch testing with chromate (in chromium-sensitive subjects) to detect the minimum elicitation threshold (MET) is best done by using serial dilutions of Cr(III) and Cr(VI). • Chromium can cause lipid peroxidation, nephrotoxicity, and affect the immune system. • Reduction or elimination of exposure is the best method for prevention of chromium-induced contact allergy.
CITATION STYLE
Cary, J. H., Maibach, H. I., Burrows, D., & Hostynek, J. J. (2019). Chromium. In Kanerva’s Occupational Dermatology (pp. 647–660). Springer International Publishing. https://doi.org/10.1007/978-3-319-68617-2_44
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