Reliability of corneal dynamic scheimpflug analyser measurements in virgin and post-PRK eyes

Abstract

Purpose: To determine the measurement reliability of CorVis ST, a dynamic Scheimpflug analyser, in virgin and post-photorefractive keratectomy (PRK) eyes and compare the results between these two groups. Methods: Forty virgin eyes and 42 post-PRK eyes underwent CorVis ST measurements performed by two technicians. Repeatability was evaluated by comparing three consecutive measurements by technician A. Reproducibility was determined by comparing the first measurement by technician A with one performed by technician B. Intraobserver and interobserver intraclass correlation coefficients (ICCs) were calculated. Univariate analysis of covariance (ANCOVA) was used to compare measured parameters between virgin and post-PRK eyes. Results: The intraocular pressure (IOP), central corneal thickness (CCT) and 1stapplanation time demonstrated good intraobserver repeatability and interobserver reproducibility (ICC≥0.90) in virgin and post-PRK eyes. The deformation amplitude showed a good or close to good repeatability and reproducibility in both groups (ICC≥0.88). The CCT correlated positively with 1stapplanation time (r = 0.437 and 0.483, respectively, p<0.05) and negatively with deformation amplitude (r = -0.384 and -0.375, respectively, p<0.05) in both groups. Compared to post-PRK eyes, virgin eyes showed longer 1stapplanation time (7.29±0.21 vs. 6.96±0.17 ms, p<0.05) and lower deformation amplitude (1.06±0.07 vs. 1.17±0.08 mm, p<0.05). Conclusions: CorVis ST demonstrated reliable measurements for CCT, IOP, and 1stapplanation time, as well as relatively reliable measurement for deformation amplitude in both virgin and post-PRK eyes. There were differences in 1stapplanation time and deformation amplitude between virgin and post-PRK eyes, which may reflect corneal biomechanical changes occurring after the surgery in the latter.