THE ELECTROLYTE CONCENTRATION OF HUMAN GASTRIC SECRETION

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Abstract

The secretion by the stomach of hydrochloric acid, sodium, potassium and chloride has been studied in normal human subjects and in patients suffering from peptic ulcer. A close inverse relationship was demonstrated between the concentration of acid and sodium, and a direct relationship between potassium concentration and the rate of secretion of gastric juice. It is suggested that H and Na ions may share a secretory pathway, and that K concentration represents a part of the process of water secretion. These findings were consistent in over 300 samples of gastric juice, obtained without stimulation, and after stimulation with histamine or insulin. © 1960 The Physiological Society

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Strong, J. A., Cameron, D., & Riddell, M. J. (1960). THE ELECTROLYTE CONCENTRATION OF HUMAN GASTRIC SECRETION. Quarterly Journal of Experimental Physiology and Cognate Medical Sciences, 45(1), 1–11. https://doi.org/10.1113/expphysiol.1960.sp001428

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