Breakthroughs on many fronts have provided strong evidence to support synaptic dysfunction as a causal factor for neuropsychiatric diseases. Genetic studies have identified variants implicated in novel biological and synaptic pathways, and animal and patient-derived induced pluripotent stem cell-based models have allowed mechanistic investigations of synaptic dysfunction in pathological processes.
CITATION STYLE
Wang, X., Christian, K. M., Song, H., & Ming, G. li. (2018, January 31). Synaptic dysfunction in complex psychiatric disorders: From genetics to mechanisms. Genome Medicine. BioMed Central Ltd. https://doi.org/10.1186/s13073-018-0518-5
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