Serum Lipid Profile in Pregnancy and Postpartum Severe Preeclampsia

Abstract

Objective: To investigate the associationbetween serum lipid profile (total cholesterol, triglyceride, HDL, LDL, VLDL) andpregnancy as well as postpartum severe preeclampsia. Methods: This is a cross-sectional comparative analytic study Results: From 28 preeclampsia subject were found, mean value of systole 165.36 mmHg and 105.71 diastole. Serum lipid profile in pregnancy and postpartum has a significant differencesandcorrelatedwithpreeclampsia,totalcholesterol 234.5 mg/dl and 192.71 mg/dl, p=0.000; medium positive in pregnancy with systole r=0.461; p=0.013, weak positive with diastole r=0.380; p=0.046; postpartum with systole medium positive r=0.615; p=0.001, and weak positive with diastole r=0.317; p=0.100. LDL 140.5 mg/dl and 102.5 mg/ dl, p=0.000; pregnancy and systole r=0.446; p=0,017; and postpartum were medium positive r=0.546; p=0.003. HDL 51.5 mg/dl and 43.5 mg/dl, p=0.003; not correlated with BP. Triglyceride 268.89 mg/dl and 208.96 mg/dl, p=0.000; pregnancy r=0.516; p=0.005; postpartum r= 0.515; p=0.005 has medium correlation with systole. VLDL 53.78 mg/dl and 41.79, p=0.000; pregnancy r=0.461; p=0.013 systole medium positive; r=0.380; p=0.046 diastole weak positive; postpartum r=0,615; p=0,001 systole strong positive. Conclusions:Allparameterofserumlipidprofileinpregnancy and postpartum had significant differences and related with severe preeclampsia. Total cholesterol, LDL, triglyceride, and VLDL correlated with BP in severe preeclampsia.