Definition: Intermediate bone tumor with a variable and unpredictable potential for growth, consisting of a background of undifferentiated mononuclear stromal cells with uniformly scattered osteoclast-like multinucleated giant cells. Over 90% of GCTs present histone variants in the H3F3A gene.
CITATION STYLE
Manfrini, M. (2019). Giant cell tumor. In Diagnosis of Musculoskeletal Tumors and Tumor-like Conditions: Clinical, Radiological and Histological Correlations - the Rizzoli Case Archive (pp. 101–105). Springer International Publishing. https://doi.org/10.1007/978-3-030-29676-6_22
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