Dystonia is a rare manifestation of multiple sclerosis (MS), but it always interferes with the functional performance and quality of life. We report a rare case of long-lasting paroxysmal dystonia associated with MS. The patient was a 40-year-old woman with relapsing- remitting MS for 6 years. During the latest attack of MS, she suffered from long-lasting paroxysmal dystonia in her left hand. Despite treatment with pulse high-dose intravenous methylprednisolone, interferon, and baclofen, along with occupational therapy, the dystonia persisted and significantly bothered her daily activities. Finally, she was treated with oral acetazolamide (250 mg, three times a day for 4 days), which was very effective for the control of her dystonia. The dystonic movement subsided without recurrence in a follow-up of 17 months. We advocate this effective and safe treatment for patients with paroxysmal dystonia associated with MS. © 2013 Hsieh et al, publisher and licensee Dove Medical Press Ltd.
CITATION STYLE
Hsieh, P. C., Chen, S. M., Guo, Y. H., Kuan, T. S., Yen, W. J., Chang, W. C., & Lin, Y. C. (2013). Effect of acetazolamide for long-lasting paroxysmal dystonia in a patient with multiple sclerosis: A case report and review of literature. Neuropsychiatric Disease and Treatment, 9, 445–448. https://doi.org/10.2147/NDT.S43688
Mendeley helps you to discover research relevant for your work.