Vias de síntese linear e convergente: qual é mais verde?

Abstract

Recebido em 9/1/11; aceito em 18/3/11; publicado na web em 10/6/11 LINEAR VS CONVERGENT SYNTHETIC PATHWAY-WHICH IS GREENER? A comparative study of a convergent and the linear synthetic pathway with respect to their relative greenish allowed the quantification of the advantages of the former with respect to atomic productivity as well as robustness. The calculations show that convergent pathways provide a decrease of costs together with a decrease of E factor and an increase of atomic economy which means that greenish is accompanied by an economic advantage. The influence of other features of the convergent pathways synthesis on the improvement of the synthesis greenish is discussed qualitatively.