Spondyloarthritis

Abstract

The term spondyloarthritis (SpA) defines a family of diseases with overlapping clinical features that reflect shared genetic risk factors and pathophysiology. Inflammation of the spine is a core feature of these disorders. Spondyloarthritis and spondyloarthropathy are often used synonymously. Diseases typically included under the SpA umbrella are ankylosing spondylitis (AS), psoriatic arthritis (PsA), reactive arthritis (ReA), SpA associated with inflammatory bowel disease, and undifferentiated SpA.