piRNAs and siRNAs collaborate in Caenorhabditis elegans genome defense

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Abstract

Caenorhabditis elegans piRNAs promote genome surveillance by triggering siRNA-mediated silencing of nonself DNA in competition with licensing programs that support endogenous gene expression.

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Billi, A. C., Freeberg, M. A., & Kim, J. K. (2012). piRNAs and siRNAs collaborate in Caenorhabditis elegans genome defense. Genome Biology. https://doi.org/10.1186/gb-2012-13-7-164

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