Infliximab-Induced Lupus in Crohn’s Disease

  • Choi S
  • Kim S
  • Kim H
  • et al.
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Abstract

An UASB+Anoxic/Oxic (A/O) system was introduced to treat a mature landfill leachate with low carbon-to-nitrogen ratio and high ammonia concentration. To make the best use of the biodegradable COD in the leachate, the denitrification of NOx --N in the recirculation effluent from the clarifier was carried out in the UASB. The results showed that most biodegradable organic matters were removed by the denitrification in the UASB. The NH4 +-N loading rate (ALR) of A/O reactor and operational temperature was 0.28-0.60 kg NH4 +-N/(m3??d) and 17-29??C during experimental period, respectively. The short-cut nitrification with nitrite accumulation efficiency of 90%-99% was stabilized during the whole experiment. The NH4 +-N removal efficiency varied between 90% and 100%. When ALR was less than 0.45 kg NH4 +-N/(m3??d), the NH4+-N removal efficiency was more than 98%. With the influent NH4+-N of 1200-1800 mg/L, the effluent NH4 +-N was less than 15 mg/L. The shortcut nitrification and denitrification can save 40% carbon source, with a highly efficient denitrification taking place in the UASB. When the ratio of the feed COD to feed NH4 +-N was only 2-3, the total inorganic nitrogen (TIN) removal efficiency attained 67%-80%. Besides, the sludge samples from A/O reactor were analyzed using FISH. The FISH analysis revealed that ammonia oxidation bacteria (AOB) accounted for 4% of the total eubacterial population, whereas nitrite oxidation bacteria (NOB) accounted only for 0.2% of the total eubacterial population. ?? 2007 The Research Centre for Eco-Environmental Sciences, Chinese Academy of Sciences.

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APA

Choi, S. J., Kim, S., Kim, H.-Y., Lee, Y., Hyun, D.-G., Yang, S.-K., & Kim, Y.-G. (2019). Infliximab-Induced Lupus in Crohn’s Disease. The Korean Journal of Medicine, 94(3), 303–307. https://doi.org/10.3904/kjm.2019.94.3.303

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