Determine whether or not improvements to the calibration procedure for a novel dual-energy x-ray mammography technique improve the uniformity, accuracy, and/or reproducibility of the measured breast composition. The long-term goal of this project is to develop a technique that will improve the specificity of mammography diagnosis. Energy dependent corrections for light-field, dark-field, and Heel effect were made for each measurement. A total of 20 women who were scheduled for additional imaging prior to biopsy underwent an additional dual-energy/low dose full-field digital mammography scan as part of a pilot study investigating the use of breast composition measures in mammography. The estimated water/lipid/protein content of suspicious lesions were measured. The modified x-ray calibration procedure resulted in over a 3-fold improvement in the uniformity of a flat-field calibration phantom with known breast density. Some preliminary results from women are available and show that different types of breast lesions have different compositions. © 2012 Springer-Verlag Berlin Heidelberg.
CITATION STYLE
Duewer, F., Flowers, C. I., Kerlikowske, K., Malkov, S., Joe, B. N., & Shepherd, J. A. (2012). Improvements and performance of diagnostic compositional imaging using a novel dual-energy x-ray technique. In Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) (Vol. 7361 LNCS, pp. 569–574). https://doi.org/10.1007/978-3-642-31271-7_73
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