Genotyping cell-free tumor DNA in the blood to detect residual disease and drug resistance

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Abstract

DNA fragments released from cancer cells into the blood can be used to generate molecular profiles of tumors. Non-invasive 'liquid biopsies' can be used to monitor minimal residual disease and detect the emergence of drug resistance.

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Siravegna, G., & Bardelli, A. (2014, August 19). Genotyping cell-free tumor DNA in the blood to detect residual disease and drug resistance. Genome Biology. BioMed Central Ltd. https://doi.org/10.1186/s13059-014-0449-4

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