Is there emergence of clinical HBV resistance under long-term HBV combination therapy? A challenging case report

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Abstract

A first case of clinical tenofovir (TDF) HBV resistance in an HIV/HBV coinfected patient who developed an acute flare of hepatitis B is reported. The clinical course was accompanied by signs of acute liver failure after being on successful HBV treatment with tenofovir and persistently undetectable HBV-DNA viral load for over five years. © 2010 by the authors.

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Schewe, K., Noah, C., Sirma, H., Schmiedel, S., van Lunzen, J., Rockstroh, J. K., & Schildgen, O. (2010). Is there emergence of clinical HBV resistance under long-term HBV combination therapy? A challenging case report. Viruses, 2(8), 1564–1570. https://doi.org/10.3390/v2081564

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