Proteomic studies have the potential to comprehensively define the composition of organelles but are limited by the organellar cross-contamination that arises during subcellular fractionation. Comparative proteomics of organellar subfractions can mitigate these problems, as demonstrated by a recent study involving the nuclear envelope.
CITATION STYLE
Schrimer, E. C., & Gerace, L. (2002). Organellar proteomics: The prizes and pitfalls of opening the nuclear envelope. Genome Biology.
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